LocusFocus:简单求和方法在测试GWAS与任何其他SNP级别数据(例如eQTL数据)的共定位中的应用

上传者: 42181888 | 上传时间: 2023-08-25 13:03:29 | 文件大小: 47.91MB | 文件类型: ZIP
焦点 使用GTEx的eQTL协会结果探索GWAS结果 该Web应用程序将通过与整合到单个交互式图中,并通过应用进行可视化,使GWAS结果的探索和注释能够评估哪些基因和组织是GWAS信号最可能的候选者。结果显示在热图上。 此外,用户可以上传其他数据集以测试共定位。 例如,可以上传其他表型关联(即PheWAS)以评估多效性或其他来源的eQTL数据,以获得正式的共定位测试和数据可视化。 LD信息是使用1000 Genomes Project上的PLINK计算得出的,以便在给定领先SNP的情况下查看LD。 默认的销售线索SNP是顶部的SNP。 eQTL关联结果已本地存储在MongoDB数据库中。 完整文档可从。 可以通过访问该应用程序。

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