sciPath:通过整合途径改善单细胞RNA-seq聚类

上传者: 42134878 | 上传时间: 2022-06-23 17:08:04 | 文件大小: 23.76MB | 文件类型: ZIP
科学路径 通过整合途径改善单细胞RNA-seq聚类 内容描述 我们设计了一个框架(sciPath),以通过整合途径来研究现有单细胞聚类的准确性和鲁棒性,包括10种最新的单细胞聚类方法和4种途径数据库,途径整合方法和一套完整的评估指标。 准备工作 1.数据集演示数据集保存在".//Demo_data" ,包括scRNA-seq矩阵(".//Demo_data//matrix") ,路径(".//Demo_data//pathway")和单元格标签(".//Demo_data//label") 。 2.软件包安装脱机软件包和联机软件包的安装代码保存在".//package//package_install.R" 。 代号 1. clustering_by_gene_only.R 仅考虑基因水平信息的单细胞聚类,包括(1)K均值,(2)分级,(3)光谱,(4)DBSCAN,(5)SC3,(6)

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