PPIXpress:转录本表达中的特定蛋白质相互作用网络-开源

上传者: 42149153 | 上传时间: 2021-04-29 13:04:49 | 文件大小: 17.3MB | 文件类型: ZIP
尽管蛋白质间相互作用网络是现代系统生物学中普遍存在的组成部分,但为将其拓扑结构调整为研究中的实际细胞条件所做的努力相对较少。 由于将网络简化为表达基因的子集仅会刮擦高等生物的调控能力,因此我们提出了先进的方法PPIXpress,该方法可利用转录本水平的表达数据,从而能够揭示基因组中的变化。选择性剪接引起的蛋白质连接性。 原始出版物可在https://bioinformatics.oxfordjournals.org/content/32/4/571上找到。

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