pharmsignal:药理数据中的信号检测(药物警戒性)-源码

上传者: 42117267 | 上传时间: 2021-03-22 18:08:21 | 文件大小: 36KB | 文件类型: ZIP
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pharmsignal 药理数据中的安全信号检测(药物警戒)。 报告奇数比(ROR),比例报告比(PRR),贝叶斯置信度传播神经网络信息组件(BCPNN IC,MCMC和正态近似)的实现以及序列对称性分析(SSA)的实现。 背景 药品不良事件的信号检测通常需要分析下表中列出的计数数据。 Event(s) X Event(s) Y Drug(s) A 一种 b Drug(s) B C d 该软件包具有计算以下信号检测方法的功能: ror_signal() : ror_signal()为100(1-alpha/2)% ROR ror_signal() :置信区间为100(1-alpha/2)% PRR bcpnn_norm_signal() :BCPNN IC使用Gould(2003)的IC后验分布的“精确”期望和方差,使用正态近似值构造log_2尺度上的100(1-

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