DomFun:使用蛋白质结构域和功能注释之间的关联进行蛋白质功能预测

上传者: 42116604 | 上传时间: 2022-10-28 15:42:40 | 文件大小: 32KB | 文件类型: ZIP
DomFun DomFun是使用系统方法将功能分配给未知蛋白质的新系统,而无需考虑其序列但其功能域与功能系统相关联。 它使用在蛋白质结构域和功能注释之间计算的关联作为训练数据集,并通过查找蛋白质的结构域以及它们是否已与功能注释(在GO分子功能,生物学过程,KEGG和Reactome途径术语中)相关联,对蛋白质进行预测(使用UniProt标识符)。 )。 安装 将此行添加到您的应用程序的Gemfile中: gem 'DomFun' 然后执行: $ bundle 或自己安装为: $ gem install DomFun 用法 要使用DomFun,有必要计算蛋白质结构域和功能注释之间的关联。 为此,请使用NetAnalyzerRubygem( ),选择最适合您数据的关联索引。 一旦计算出这些关联,它们将用于训练DomFun并预测一组功能未知的蛋白质(赋予UniProt标识符)。 在

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